VONGRAEVENITZ A
J Bacteriol. 1964 Oct;88(4):960-4. doi: 10.1128/JB.88.4.960-964.1964.
von Graevenitz, Alexander (Yale University, New Haven, Conn.). Genetic transfer of streptomycin and aminopropanolstreptomycin resistance. J. Bacteriol. 88:960-964. 1964.-Transduction and conjugation experiments with Staphylococcus aureus and Escherichia coli suggest that resistance to streptomycin (S) and aminopropanolstreptomycin (A) is due to the same mutation arising in a single step at the locus str. The high occurrence of S(r)A(s) cells (1 to 3%) in an S(r)A(r) population was noted. From genetic crosses of S(r)A(s) with S(s)A(s) cells, it can be concluded that there is a suppressor locus su-A adjacent to, but separable by recombination from, the str locus. It modifies the genotype S(r)A(r) to the phenotype S(r)A(s).
冯·格雷费尼茨,亚历山大(耶鲁大学,康涅狄格州纽黑文)。链霉素和氨基丙醇链霉素抗性的基因转移。《细菌学杂志》88:960 - 964。1964年。——用金黄色葡萄球菌和大肠杆菌进行的转导和接合实验表明,对链霉素(S)和氨基丙醇链霉素(A)的抗性是由于在str位点一步产生的相同突变所致。在S(r)A(r)群体中注意到S(r)A(s)细胞的高发生率(1%至3%)。从S(r)A(s)与S(s)A(s)细胞的遗传杂交中可以得出结论,存在一个与str位点相邻但可通过重组分离的抑制基因座su - A。它将基因型S(r)A(r)改变为表型S(r)A(s)。