JACOBS S I, WILLIS A T
J Clin Pathol. 1964 Nov;17(6):612-6. doi: 10.1136/jcp.17.6.612.
Five hundred and fifty-two strains of Staphylococcus aureus of hospital origin were resistant to penicillin, streptomycin, and tetracycline. Of these, 298 were also resistant to neomycin and kanamycin, and this resistance was related to pigment production on glycerol monoacetate agar, the production of beta-lysin, the absence of fibrinolytic and proteolytic activity, and to phage susceptibility. The use of physiological markers, the inadequacy of phage typing, and the possible reasons for the emergence of neomycin-resistant staphylococci are discussed.
552株医院源性金黄色葡萄球菌对青霉素、链霉素和四环素耐药。其中,298株对新霉素和卡那霉素也耐药,这种耐药性与在单乙酸甘油酯琼脂上产生色素、产生β-溶血素、缺乏纤维蛋白溶解和蛋白水解活性以及噬菌体敏感性有关。文中讨论了生理标记的应用、噬菌体分型的不足以及新霉素耐药葡萄球菌出现的可能原因。