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松弛素与产后母猪产奶量低无关。

Relaxin is not associated with poor milk yield in the postpartum sow.

作者信息

Porter D G, Friendship R M, Ryan P L, Wasnidge C

机构信息

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph.

出版信息

Can J Vet Res. 1992 Jul;56(3):204-7.

PMID:1423055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1263539/
Abstract

Porcine relaxin (pRXN) titers were measured in 109 plasma samples drawn between 24 and 120 h post-partum from good (n = 34), and poor (n = 25) milking sows and from sows (n = 12) exhibiting overt signs of hypogalactia located on six swine farms in Ontario. Mean plasma pRXN titers among the three groups at 24 h post-partum were not significantly different although there was considerable variation. By 48 h however, the pRXN titers had declined markedly in all groups and between 72 and 120 h, pRXN was cleared from the plasma of all sows examined except one hypogalactic animal that had a titer of 1.13 ng/mL at 96 h. These results suggest that, although pRXN may be identifiable in the corpora lutea during the puerperium, it does not contribute to either hypogalactia or poor lactational performance in sows. The data also encourage the view that pRXN could be used at farrowing without deleterious effects on suckling.

摘要

在安大略省六个养猪场,从产后24至120小时采集的109份血浆样本中检测了猪松弛素(pRXN)滴度,这些样本来自泌乳良好的母猪(n = 34)、泌乳差的母猪(n = 25)以及表现出明显少乳迹象的母猪(n = 12)。产后24小时时,三组母猪的血浆pRXN平均滴度虽有相当大的差异,但无显著不同。然而,到48小时时,所有组的pRXN滴度均显著下降,在72至120小时期间,除一头少乳母猪在96小时时滴度为1.13 ng/mL外,所有检测母猪的血浆中pRXN均已清除。这些结果表明,尽管在产褥期黄体中可能可识别出pRXN,但它对母猪的少乳或泌乳性能不佳并无影响。这些数据还支持这样一种观点,即分娩时使用pRXN对哺乳无有害影响。

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1
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2
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本文引用的文献

1
Relaxin improves the coordination of rat myometrial activity in vivo.
Biol Reprod. 1980 Dec;23(5):899-903. doi: 10.1095/biolreprod23.5.899.
2
Relaxin levels in the maternal plasma of pigs before, during, and after parturition and before, during, and after suckling.母猪分娩前、分娩期间、分娩后以及哺乳前、哺乳期间、哺乳后的母体血浆中松弛素水平。
Biol Reprod. 1981 Aug;25(1):65-71. doi: 10.1095/biolreprod25.1.65.
3
Effect of relaxin on parturition and frequency of live births in pigs.松弛素对猪分娩及活产频率的影响。
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4
Plasma concentrations of prolactin, progesterone, relaxin and oestradiol-17 beta in sows treated with progesterone, bromocriptine or indomethacin during late pregnancy.在妊娠后期用孕酮、溴隐亭或吲哚美辛处理的母猪中催乳素、孕酮、松弛素和雌二醇-17β的血浆浓度。
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The milk ejection reflex in the pig.猪的排乳反射。
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Relaxin affects the central control of oxytocin release.
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Plasma relaxin levels during suckling and oxytocin stimulation in the lactating sow.哺乳期母猪在哺乳和催产素刺激期间的血浆松弛素水平。
Biol Reprod. 1985 Oct;33(3):705-14. doi: 10.1095/biolreprod33.3.705.
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Effects of porcine relaxin on oxytocin release from the neurohypophysis in the anaesthetized lactating rat.猪松弛素对麻醉泌乳大鼠神经垂体催产素释放的影响。
J Endocrinol. 1986 Jun;109(3):393-7. doi: 10.1677/joe.0.1090393.
10
Plasma steroid, relaxin and dihydro-keto-prostaglandin F-2 alpha changes in the minipig in relation to myometrial electrical and mechanical activity in the pre-partum period.小型猪产前血浆类固醇、松弛素和二氢酮前列腺素F-2α变化与子宫肌层电活动和机械活动的关系
J Reprod Fertil. 1988 Jul;83(2):553-64. doi: 10.1530/jrf.0.0830553.