CUDKOWICZ L
Can Med Assoc J. 1965 Jan 16;92(3):111-5.
Cardiorespiratory studies in 13 young females and 11 middle-aged men with localized acute pulmonary tuberculosis revealed evidence of significant resting hyperventilation and reduction in the dynamics of ventilation indicative of restrictive lung disease. Indices of intrapulmonary mixing and pulmonary diffusing capacities were normal, as were alveolar-arterial pCO(2) gradients.The ventilation/perfusion ratios were slightly elevated in both groups, while pulmonary artery pressure and total pulmonary vascular resistance (TPVR) showed a rise in the males only.Both groups showed an increase in actual QBF flows and a resultant significant decrease in arterial pO(2), which suggests that the areas of tuberculous infection are metabolically active.
对13名患有局部急性肺结核的年轻女性和11名中年男性进行的心肺研究表明，有证据显示静息时存在明显的通气过度，且通气动力学降低，提示存在限制性肺病。肺内混合指数和肺弥散能力正常，肺泡-动脉血二氧化碳分压差也正常。两组的通气/灌注比均略有升高，而肺动脉压和总肺血管阻力仅在男性中升高。两组的实际肺血流量均增加，导致动脉血氧分压显著下降，这表明结核感染区域代谢活跃。
