Esyrev O V, Murzakhmetova M K, Omarova R D
Tsitologiia. 1976 Nov;18(11):1378-82.
A slow decline of responses was obtained after acetylcholine and KCl-stimulation of musculus rectus abdominis of the lake frog in the presence of antymicin A (0.27 mcg/ml). Dinitrophenol (up to 6.7.10(-4) M) as well as antymicin A inhibited the muscle contractility, with the effect being reversible. Muscle contraction ensued the application of dinitrophenol in concentration more than 6.7.10(-4)M. Decurarization ability of dinitrophenol was established. Mechanisms of disruption of the excitation--contraction coupling due to metabolic inhibitors are discussed.
在抗霉素A（0.27微克/毫升）存在的情况下，对湖蛙腹直肌进行乙酰胆碱和氯化钾刺激后，反应出现缓慢下降。二硝基苯酚（高达6.7×10⁻⁴ M）以及抗霉素A均抑制肌肉收缩力，且这种作用是可逆的。当二硝基苯酚浓度超过6.7×10⁻⁴ M时，肌肉会出现收缩。已证实二硝基苯酚具有脱箭毒作用。文中讨论了代谢抑制剂导致兴奋 - 收缩偶联破坏的机制。
