Höpker W W, Nüssel E, Prawitz R
Virchows Arch A Pathol Anat Histol. 1977 Jul 11;374(4):317-38. doi: 10.1007/BF00432654.
Starting from generalized theories of the arteriosclerosis, a comprehensive model of factor analysis is presented which considers the clinical risk spectrum of coronary heart disease as presently known. Arteriosclerosis and morphological findings are also included in the analysis. A differentiation is made between "progressive remification" and "multiple variable" patterns, which combine the clinical risks in a specific structure. Fractions of unknown influencing factors could be estimated quantitatively and qualitatively in such a manner that suggestions concerning the huge dependency of time and the progressive increase with age could be determined.
从动脉粥样硬化的广义理论出发,提出了一种综合的因素分析模型,该模型考虑了目前已知的冠心病临床风险谱。分析中还纳入了动脉硬化和形态学发现。区分了“渐进性细化”和“多变量”模式,它们以特定结构组合临床风险。未知影响因素的比例可以通过定量和定性的方式进行估计,从而能够确定关于时间的巨大依赖性以及随年龄的逐渐增加的相关建议。