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冠心病中的冠状动脉粥样硬化及危险因素(作者译)

[Coronary arteriosclerosis and risk factors in coronary heart disease (author's transl)].

作者信息

Höpker W W, Nüssel E, Pasternak G, Hofmann W

出版信息

Virchows Arch A Pathol Anat Histol. 1977 Jun 3;374(2):131-56. doi: 10.1007/BF00432897.

Abstract

A large number of cases were tested for the relevance of clinical risk factors in coronary heart disease with regard to coronary arteriosclerosis (atheroma, fibrosis; five different locations). The method applied was VARIMAX-rotated factor analysis. The resulting factors were interpreted as the multiple variables structures which are in different relationships to the risk criterion, coronary heart disease, and morphological vascular diagnosis of the coronary arteries. The importance of the known risk of the vascular diagnosis was estimated and the reterance of the clinically influencing criterion was discussed. It appears that in spite of limited methodology additional morphological criteria are required in order to be able to explain heart infarction which does not involve the epicardial branches of the coronary vascular system.

摘要

对大量病例进行了关于冠心病临床危险因素与冠状动脉粥样硬化(动脉粥样瘤、纤维化;五个不同部位)相关性的检测。所应用的方法是方差最大化旋转因子分析。所得出的因子被解释为与风险标准、冠心病以及冠状动脉形态学血管诊断处于不同关系的多变量结构。评估了血管诊断已知风险的重要性,并讨论了临床影响标准的相关性。尽管方法有限,但似乎仍需要额外的形态学标准,以便能够解释不涉及冠状动脉血管系统心外膜分支的心肌梗死。

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