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[将无氧糖酵解速率增加作为失血性休克中缺氧的指标]

[Increase in the rate of anaerobic glycolysis as an index of hypoxia in hemorrhagic shock].

作者信息

Zinov'ev Iu V, Kozlov S A, Ovsiannikova E Iu

出版信息

Vopr Med Khim. 1977 Mar-Apr;23(2):151-5.

PMID:142369
Abstract

A rate of anaerobic glycolysis and the activity of several enzymes involved were studied in brain, heart, liver and small intestine of rabbits in hemorrhagic shock. In hemorrhagic shock at 45 mm of m. c. the rate of glycolysis was increased in liver tissue and intestine, at 35 mm of m.c.--in liver tissue, intestine and brain, at 26 mm of m.c.--in all the tissues studied. The enzymatic activity did not alter markedly. The possible mechanism of the increased rate of anaerobic glycolysis is discussed.

摘要

研究了失血性休克家兔脑、心脏、肝脏和小肠的无氧糖酵解速率以及几种相关酶的活性。在平均动脉压为45mmHg的失血性休克中,肝脏组织和小肠的糖酵解速率增加;在平均动脉压为35mmHg时,肝脏组织、小肠和脑的糖酵解速率增加;在平均动脉压为26mmHg时,所有研究组织的糖酵解速率均增加。酶活性没有明显改变。文中讨论了无氧糖酵解速率增加的可能机制。

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