Ovsiannikova E Iu, Kozlov S A, Zinov'ev Iu V
Zh Evol Biokhim Fiziol. 1976 Sep-Oct;12(5):434-8.
In rabbits and albino rats, studies have been made on the resistance to high altitude hypoxia and acute blood loss, the rate of anerobic glycolysis and the activity of some enzymes of energy metabolism. It was shown that as compared to rabbits, the rats are more resistant to hypoxia, but less resistant to acute blood loss. Higher resistance of rats to hypoxia is due to the 1.5 times rate of anaerobic glycolysis in their brain as compared to that of rabbits. Their lower resistance to the blood loss is associated with the fact that the rate of anaerobic glycolysis in the heart of rats is 8 times lower. It is concluded that the resistance to high altitude hypoxia depends mainly on the anaerobic metabolism of the brain, whereas tia depends mainly on the anaerobic metabolism of the brain, whereas the resistance to acute blood loss depends mainly on the anaerobic metabolism of the heart.
在兔子和白化大鼠身上,已经对它们对高原缺氧和急性失血的抵抗力、无氧糖酵解速率以及一些能量代谢酶的活性进行了研究。结果表明,与兔子相比,大鼠对缺氧的抵抗力更强,但对急性失血的抵抗力较弱。大鼠对缺氧的较高抵抗力是由于其大脑中的无氧糖酵解速率是兔子的1.5倍。它们对失血的较低抵抗力与以下事实有关:大鼠心脏中的无氧糖酵解速率低8倍。得出的结论是,对高原缺氧的抵抗力主要取决于大脑的无氧代谢,而对急性失血的抵抗力主要取决于心脏的无氧代谢。