莫洛尼病毒诱发的小鼠白血病：特异性抗原的体外测定
MOLONEY VIRUS-INDUCED LEUKEMIAS OF MICE: MEASUREMENT IN VITRO OF SPECIFIC ANTIGEN.
作者信息
HAUGHTON G
出版信息
Science. 1965 Jan 29;147(3657):506-7. doi: 10.1126/science.147.3657.506.
PMID:14237205
Abstract
A modified test for cytotoxic antibody may be used to measure antibody directed against the tumor-specific antigen of leukemias of mice induced by Moloney virus; cell death is detected by liberation of (51)Cr. An inhibition test based on this technique permits accurate measurement of tumor-specific antigen in cells and subcellular fractions.
摘要
一种改良的细胞毒性抗体检测方法可用于检测针对由莫洛尼病毒诱导的小鼠白血病肿瘤特异性抗原的抗体；通过（51）铬的释放来检测细胞死亡。基于该技术的抑制试验可精确测量细胞和亚细胞组分中的肿瘤特异性抗原。
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