活体肌肉的核磁共振研究

NUCLEAR MAGNETIC RESONANCE STUDIES OF LIVING MUSCLE.

作者信息

BRATTON C B, HOPKINS A L, WEINBERG J W

出版信息

Science. 1965 Feb 12;147(3659):738-9. doi: 10.1126/science.147.3659.738.

DOI:10.1126/science.147.3659.738

PMID:14242018

Abstract

Measurements of nuclear magnetic relaxation times for protons of water in living skeletal frog muscle show the transverse relaxation time, T(2), increases when a muscle contracts isometrically. This result and other experimental data suggest that a fraction of the intracellular water molecules have restricted rotational freedom and that this fraction decreases when contraction occurs.

摘要

对活的青蛙骨骼肌中水分子质子的核磁共振弛豫时间的测量表明，当肌肉进行等长收缩时，横向弛豫时间T(2)会增加。这一结果和其他实验数据表明，一部分细胞内水分子的旋转自由度受到限制，并且当发生收缩时，这部分水分子的比例会降低。