EVANS A R
J Clin Pathol. 1965 Jan;18(1):54-62. doi: 10.1136/jcp.18.1.54.
The clinical histories and post-mortem findings in five cases of neuroblastoma are described, and an account given of the microscopic characteristics of the tumours. In four of the cases the tumour was present at birth and was probably so in the fifth case. In only one case was the presence of the malignant tumour a significant factor in causing death. The differential diagnosis of such tumours is discussed.The accumulated evidence of many recorded cases suggests that neuroblastoma, becoming manifest in the early months or weeks of life, and congenital tumour, would be included in such a group, and has an appreciably better prognosis than has this same tumour when it becomes manifest in later childhood. The literature is briefly reviewed to illustrate this aspect of prognosis and possible reasons for it are indicated.
本文描述了5例神经母细胞瘤的临床病史和尸检结果，并阐述了肿瘤的微观特征。其中4例肿瘤在出生时就已存在，第5例可能也是如此。只有1例中，恶性肿瘤的存在是导致死亡的重要因素。文中讨论了此类肿瘤的鉴别诊断。许多已记录病例的累积证据表明，在生命最初几个月或几周内出现症状的神经母细胞瘤以及先天性肿瘤，应归为同一组，其预后明显优于在儿童后期出现症状的同类型肿瘤。本文简要回顾了相关文献以说明预后的这一方面，并指出了可能的原因。
