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A NEW, POTENT AND SPECIFIC SEROTONIN INHIBITOR, (SQ 10,643) 2'-(3-DIMETHYLAMINOPROPYLTHIO) CINNAMANILIDE HYDROCHLORIDE: ANTISEROTONIN ACTIVITY ON UTERUS AND ON GASTROINTESTINAL, VASCULAR, AND RESPIRATORY SYSTEMS OF ANIMALS.

作者信息

RUBIN B, PIALA J J, BURKE J C, CRAVER B N

出版信息

Arch Int Pharmacodyn Ther. 1964 Nov 1;152:132-43.

PMID:14248340
Abstract
摘要

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1
A NEW, POTENT AND SPECIFIC SEROTONIN INHIBITOR, (SQ 10,643) 2'-(3-DIMETHYLAMINOPROPYLTHIO) CINNAMANILIDE HYDROCHLORIDE: ANTISEROTONIN ACTIVITY ON UTERUS AND ON GASTROINTESTINAL, VASCULAR, AND RESPIRATORY SYSTEMS OF ANIMALS.一种新型、强效且特异性的血清素抑制剂，（SQ 10,643）2'-（3-二甲基氨基丙硫基）肉桂酰苯胺盐酸盐：对动物子宫及胃肠、血管和呼吸系统的抗血清素活性。
Arch Int Pharmacodyn Ther. 1964 Nov 1;152:132-43.
2
[ANTI-SEROTONIN ACTION AND OTHER PHARMACOLOGICAL EFFECTS OF SOME ANALOGUES OF NATURAL ERGOT ALKALOIDS].[天然麦角生物碱某些类似物的抗血清素作用及其他药理效应]
Therapie. 1964 May-Jun;19:733-42.
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ANTIPHOGISTIC EFFECTS OF ANTISEROTONIN (SQ 10,643) AND AMINOPYRINE IN RATS VERSUS ENDOTOXIN AND OTHER AGENTS.抗血清素（SQ 10,643）和氨基比林对大鼠内毒素及其他制剂的抗炎症作用
Proc Soc Exp Biol Med. 1965 Jun;119:438-43. doi: 10.3181/00379727-119-30204.
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PRESENCE OF A SLOW-CONTRACTION INDUCING MATERIAL IN FLUID COLLECTED FROM THE RAT PAW OEDEMA INDUCED BY SEROTONIN.从血清素诱导的大鼠爪水肿中收集的液体中存在一种诱导缓慢收缩的物质。
Experientia. 1965 Jan 15;21:34-5. doi: 10.1007/BF02136369.
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[EFFECT OF SOME ANTISEROTONIN DRUGS ON BLOOD COAGULATION].[某些抗血清素药物对血液凝固的影响]
Acta Physiol Pol. 1963 Nov-Dec;14:645-52.
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[COMPARATIVE STUDY OF TRYPTAMINE BLOCKING AGENTS].
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INCREASE IN ANTI-5HT ACTIVITY BY L-METHYLATION OF CLAVINE-TYPE ERGOT ALKALOIDS.棒麦角碱型麦角生物碱的L-甲基化对抗5-羟色胺活性的增强作用。
Jpn J Pharmacol. 1964 Mar;14:107-8. doi: 10.1254/jjp.14.107.
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THE EFFECT OF DIBENZHEPTROPINE CITRATE ON THE TONE OF THE BRONCHIAL MUSCLES.柠檬酸二苯庚托品对支气管肌肉张力的影响
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2'-(3-DIMETHYLAMINOPROPYLTHIO)CINNAMANILIDE AND RELATED COMPOUNDS: A NEW CLASS OF POTENT AND RELATIVELY SPECIFIC SEROTONIN INHIBITORS.2'-（3-二甲基氨基丙基硫代）肉桂酰苯胺及相关化合物：一类新型强效且相对特异的血清素抑制剂
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BENZQUINAMIDE: A CENTRALLY MEDIATED ANTAGONIST OF HISTAMINE-AND ACETYLCHOLINE-INDUCED BRONCHOCONSTRICTION.苄喹酰胺：一种组胺和乙酰胆碱诱导的支气管收缩的中枢介导拮抗剂。
Arch Int Pharmacodyn Ther. 1965 Mar;154:148-54.

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Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy.抗严重急性呼吸综合征冠状病毒化学、生物学及化疗研究进展
Annu Rep Med Chem. 2007 Feb 1;41:183-196. doi: 10.1016/S0065-7743(06)41011-3.
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Identification and evaluation of coronavirus replicase inhibitors using a replicon cell line.使用复制子细胞系鉴定和评估冠状病毒复制酶抑制剂。
Adv Exp Med Biol. 2006;581:609-13. doi: 10.1007/978-0-387-33012-9_111.
3
Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
辛那色林是严重急性呼吸综合征冠状病毒3C样蛋白酶的抑制剂，在体外能强烈降低病毒复制。
J Virol. 2005 Jun;79(11):7095-103. doi: 10.1128/JVI.79.11.7095-7103.2005.
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Evidence for a role for central 5-HT2B as well as 5-HT2A receptors in cardiovascular regulation in anaesthetized rats.中枢5-HT2B以及5-HT2A受体在麻醉大鼠心血管调节中作用的证据。
Br J Pharmacol. 1999 Oct;128(3):530-42. doi: 10.1038/sj.bjp.0702822.
5
Mediation by 5-HT3 receptors of an excitatory effect of 5-HT on dorsal vagal preganglionic neurones in anaesthetized rats: an ionophoretic study.5-羟色胺对麻醉大鼠迷走神经背核节前神经元兴奋作用的5-羟色胺3受体介导：一项离子电泳研究。
Br J Pharmacol. 1996 Aug;118(7):1697-704. doi: 10.1111/j.1476-5381.1996.tb15594.x.
6
Evidence that activation of 5-HT2 receptors in the forebrain of anaesthetized cats causes sympathoexcitation.有证据表明，麻醉猫前脑5-羟色胺2型（5-HT2）受体的激活会引起交感神经兴奋。
Br J Pharmacol. 1995 Sep;116(2):1751-6. doi: 10.1111/j.1476-5381.1995.tb16658.x.
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Indirect action of 5-hydroxytryptamine on the isolated muscularis mucosae of the guinea-pig oesophagus.5-羟色胺对豚鼠食管离体黏膜肌层的间接作用。
Br J Pharmacol. 1983 Jan;78(1):103-10. doi: 10.1111/j.1476-5381.1983.tb09368.x.
8
Discriminative stimulus properties of fenfluramine: evidence for serotonergic involvement.芬氟拉明的辨别性刺激特性：5-羟色胺参与的证据。
Psychopharmacology (Berl). 1984;83(2):172-8. doi: 10.1007/BF00429730.
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Lack of central 5-hydroxytryptamine influence on the anticonflict activity of diazepam.中枢5-羟色胺对安定抗冲突活性缺乏影响。
Psychopharmacology (Berl). 1982;78(2):156-64. doi: 10.1007/BF00432255.
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Excitation and depression of cortical neurones by 5-hydroxytryptamine.5-羟色胺对皮层神经元的兴奋与抑制作用
J Physiol. 1967 Nov;193(2):269-94. doi: 10.1113/jphysiol.1967.sp008357.