美国两种结核菌素PPD-S和RT 23的比较
A COMPARISON IN THE UNITED STATES OF AMERICA OF TWO TUBERCULINS, PPD-S AND RT 23.
作者信息
COMSTOCK G W, EDWARDS L B, PHILIP R N, WINN W A
出版信息
Bull World Health Organ. 1964;31(2):161-70.
Abstract
A comparison of PPD-S and RT 23 was carried out in three pairs of population groups. Tuberculin sensitivity was thought to have resulted, in one of each pair, almost entirely from infection with Mycobacterium tuberculosis, and in the other, from the diverse causes operating in the United States of America. Among persons with specific tuberculin sensitivity, 2.5 TU of RT 23 in a saline buffer containing Tween 80 were approximately equivalent to 5 TU of PPD-S in phosphate-buffered saline diluent. Among persons whose sensitivity appeared to have resulted from infections with organisms antigenically similar to the Battery strain of unclassified mycobacteria, 2.5 TU of RT 23 in Tween 80 gave considerably more reactions than 5 TU of PPD-S.
摘要
在三对人群组中对PPD-S和RT 23进行了比较。在每一对人群组中，一组的结核菌素敏感性被认为几乎完全是由结核分枝杆菌感染所致，而另一组则是由美国存在的多种病因引起。在具有特异性结核菌素敏感性的人群中，含吐温80的生理盐水缓冲液中2.5 TU的RT 23大约相当于磷酸盐缓冲盐水稀释液中5 TU的PPD-S。在敏感性似乎是由与未分类分枝杆菌菌组菌株抗原相似的生物体感染所致的人群中，吐温80中2.5 TU的RT 23产生的反应比5 TU的PPD-S多得多。
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