Voigt R, Voigt P, Klinger G, Schneider H J
Rofo. 1977 Jul;127(1):69-71. doi: 10.1055/s-0029-1230659.
The relationship between high dose progesterone treatment and pregnancy and dilatation of the upper urinary tract was investigated by doing intravenous urograms on eight female rabbits. Ten features of the urogram were studied. It was concluded that the administration of sex hormones to rabbits without any mechanical change in the ureters, did not lead to urographically demonstrable dilatation of the ureters. Negative findings in pregnant animals indicate that the mechanical situation in rabbits differs from that found in human pregnancy. The results are discussed with relation to the available literature.
通过对八只雌性兔子进行静脉肾盂造影,研究了大剂量孕酮治疗与妊娠及上尿路扩张之间的关系。研究了肾盂造影的十个特征。得出的结论是,在输尿管无任何机械性改变的情况下给兔子注射性激素,不会导致输尿管在尿路造影中显示出扩张。妊娠动物的阴性结果表明,兔子的机械状况与人类妊娠不同。结合现有文献对结果进行了讨论。