Rogstad K E, Dixon C A, Ahmed I H
Department of Genito-Urinary Medicine, City Hospital, Nottingham, UK.
Genitourin Med. 1992 Oct;68(5):307-8. doi: 10.1136/sti.68.5.307.
To assess whether cold coagulation to the cervix eliminates subclinical wart virus infection and to determine the effectiveness of treatment for CIN I and II, using cold coagulation, by genitourinary physicians.
Prospective study.
Department of Genitourinary medicine in a large teaching hospital.
All patients who received cold coagulation to the cervix in a 1 year period, who had not had previous treatment.
261 patients were enrolled into this study; of these, 138 (53%) patients attended for repeat colposcopy and cytology at one year. Cure rates for lesions were 66% for initial wart virus infection, 80% for CIN I and 94% for CIN II and III. Four (5%) cases in whom repeat cytology was normal had CIN which would have been missed if repeat colposcopy had not been performed at one year.
Cold coagulation is inappropriate treatment for subclinical wart virus infection of the cervix but is useful for the management of patients with CIN. Repeat colposcopy following treatment to the cervix is not necessary if cervical cytology is normal.
评估宫颈冷凝术能否消除亚临床疣病毒感染,并由泌尿生殖科医生确定冷凝术治疗CIN I和II的有效性。
前瞻性研究。
一家大型教学医院的泌尿生殖医学科。
在1年期间接受宫颈冷凝术且未曾接受过先前治疗的所有患者。
261名患者纳入本研究;其中,138名(53%)患者在1年后接受了重复阴道镜检查和细胞学检查。初始疣病毒感染的病变治愈率为66%,CIN I为80%,CIN II和III为94%。4例(5%)重复细胞学检查正常的病例患有CIN,若未在1年后进行重复阴道镜检查,这些病例将会被漏诊。
宫颈冷凝术不适用于宫颈亚临床疣病毒感染的治疗,但对CIN患者的管理有用。如果宫颈细胞学检查正常,宫颈治疗后无需重复阴道镜检查。