Barten G
Klinik für Gynäkologie und Geburtshilfe, Wilhelm-Pieck-Universität, Rostock.
Zentralbl Gynakol. 1990;112(2):99-108.
77 women with colposcopic and/or cytologic suspicious signs had been followed up 6 to 46 months. In 23 (44 per cent) out of 52 women with CIN we could observe progredience, in 19 (37 per cent) cases dysplasias and carcinoma in situ remained unchanged and in 10 (19 per cent) there was a regression. From 18 benign condylomatous lesions 8 were regredient and sones were progredient. Only in 1 out of 7 cases with benign lesions without papilloma virus infection a CIN II developed. Follow up of pregnant women demonstrated twofold more regredient findings compared with nonpregnant women. Follow up over a period of several years with colposcopic, cytologic and histologic examination in young women with CIn and childwish is possible without risk if definite management will be secured.
77名有阴道镜检查和/或细胞学可疑征象的女性接受了6至46个月的随访。在52名患有宫颈上皮内瘤变（CIN）的女性中，23名（44%）病情有进展，19名（37%）发育异常和原位癌保持不变，10名（19%）病情有消退。18例良性湿疣样病变中，8例病情消退，部分病情进展。7例无乳头瘤病毒感染的良性病变中，仅1例发展为CIN II。对孕妇的随访显示，与非孕妇相比，病情消退的情况多出一倍。如果能确保明确的治疗，对患有CIN且有生育意愿的年轻女性进行数年的阴道镜、细胞学和组织学检查随访是没有风险的。
