LAUFER H, NAKASE Y
J Cell Biol. 1965 Apr;25(1):97-102. doi: 10.1083/jcb.25.1.97.
The deoxyribonuclease (DNase) activity of the dipteran (Chironomus thummi) salivary gland, measured both enzymatically and immunochemically, increases about 7-fold with the onset of metamorphosis. The increase in DNase activity occurs at a time when the activities of other enzymes and the total protein content are decreasing. The increased DNase activity is followed by glandular destruction. It is suggested that the alterations of this activity may be regulated by the activities of specific chromosomal sites, and that the enzyme may, at least in part, account for the glandular destruction observed at the time of increased enzyme activity.
通过酶法和免疫化学方法测定，双翅目昆虫（摇蚊）唾液腺的脱氧核糖核酸酶（DNase）活性在变态开始时增加约7倍。DNase活性增加发生在其他酶活性和总蛋白含量下降的时候。DNase活性增加之后是腺体破坏。有人认为，这种活性的改变可能受特定染色体位点活性的调节，并且该酶可能至少部分地解释了在酶活性增加时观察到的腺体破坏现象。
