Kristensen F B, Mac F
Department of General Practice, University of Copenhagen, Denmark.
Int J Epidemiol. 1992 Apr;21(2):320-3. doi: 10.1093/ije/21.2.320.
The survival function of 263,322 singletons of the 1983-1987 Danish birth cohorts (262,159 liveborn and 1163 stillborn babies) with mortality distributed on functional groups of underlying causes of death is presented in two graphic forms on the basis of Kaplan-Meier estimates. About half of all first-day deaths in liveborn babies occurred during the first 4 hours. More than half of all first-week deaths happened during the first day. More than half of all deaths from 31 weeks to 76 weeks after the first day of the last menstrual period (LMP) were either fetal deaths prior to the onset of labour unexplained by fetal factors or unexplained sudden infant death syndrome (SIDS) deaths. Graphic presentation of feto-infant mortality distributed on functional cause-of-death groups improved the expression of the relative contribution and timing of the different causes of deaths. Despite a high autopsy rate and a uniform coding practice the distribution on causes of deaths from register data should be interpreted with caution. Full use of the feto-infant approach is only achieved with data which include late abortions. Thus the feto-infant approach is of special interest in countries which have registers of live births and fetal deaths from week 22 of gestation or earlier. The integration of the life table approach and analysis of underlying causes of deaths should be further explored as a way of utilizing vital statistic databases for the evaluation of perinatal care.
基于卡普兰 - 迈耶估计,以两种图表形式呈现了1983 - 1987年丹麦出生队列中263,322名单胎婴儿(262,159名活产婴儿和1163名死产婴儿)的生存函数,其死亡率按潜在死因的功能组分布。活产婴儿中约一半的首日死亡发生在最初4小时内。所有第一周死亡中超过一半发生在第一天。末次月经首日(LMP)后31周龄至76周龄期间所有死亡中,超过一半要么是分娩开始前无法用胎儿因素解释的胎儿死亡,要么是无法解释的婴儿猝死综合征(SIDS)死亡。以功能死因组分布呈现胎儿 - 婴儿死亡率,改善了不同死因的相对贡献和时间的表达。尽管尸检率高且编码做法统一,但对于登记数据中的死因分布仍应谨慎解释。只有使用包含晚期流产的数据才能充分利用胎儿 - 婴儿方法。因此,胎儿 - 婴儿方法在那些拥有妊娠22周龄或更早的活产和胎儿死亡登记册的国家特别有意义。应进一步探索将生命表方法与潜在死因分析相结合,作为利用生命统计数据库评估围产期护理的一种方式。