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正常眼压性青光眼中的弥漫性神经纤维层缺失

Diffuse nerve fiber layer loss in normal tension glaucoma.

作者信息

Yamazaki Y, Koide C, Takahashi F, Yamada H

机构信息

Department of Ophthalmology, Nihon University, Tokyo, Japan.

出版信息

Int Ophthalmol. 1992 Sep;16(4-5):247-50. doi: 10.1007/BF00917970.

DOI:10.1007/BF00917970
PMID:1428552
Abstract

14 eyes of 14 normal tension glaucoma (NTG) patients with the maximum intraocular pressure (IOP) > or = 19 mmHg and 16 eyes of 16 NTG patients with the maximum IOP < 19 mmHg were examined. All patients had a scotoma confined to the upper or lower hemifield. Eyes with the maximum IOP > or = 19 mmHg showed significantly diffuse retinal nerve fiber layer (RNFL) loss in the RNFL area corresponded to the spared visual hemifield as compared to those with the maximum IOP < 19 mmHg. The results suggests that, even in NTG, IOP may be an important factor causing optic nerve damage.

摘要

对14例最大眼压≥19mmHg的正常眼压性青光眼(NTG)患者的14只眼以及16例最大眼压<19mmHg的NTG患者的16只眼进行了检查。所有患者均有局限于上半视野或下半视野的暗点。与最大眼压<19mmHg的患者相比,最大眼压≥19mmHg的患者在与保留的视觉半视野相对应的视网膜神经纤维层(RNFL)区域显示出明显的弥漫性RNFL丢失。结果表明,即使在NTG中,眼压可能也是导致视神经损伤的一个重要因素。

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引用本文的文献

1
Intraocular pressure and central visual field of normal tension glaucoma.正常眼压性青光眼的眼压与中心视野
Br J Ophthalmol. 1997 Oct;81(10):852-6. doi: 10.1136/bjo.81.10.852.

本文引用的文献

1
Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage.筛板结构的区域差异及其与青光眼性视神经损伤的关系。
Arch Ophthalmol. 1981 Jan;99(1):137-43. doi: 10.1001/archopht.1981.03930010139020.
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Low tension glaucoma: a critical review and new material.
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Low-tension glaucoma. Enigma and opportunity.
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Correlation of asymmetric damage with asymmetric intraocular pressure in normal-tension glaucoma (low-tension glaucoma).正常眼压性青光眼(低眼压性青光眼)中不对称性损害与不对称性眼压的相关性。
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Retinal nerve fiber layer analysis by a computerized digital image analysis system.通过计算机化数字图像分析系统进行视网膜神经纤维层分析。
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Diffuse and localized glaucomatous field loss in light-sense, flicker and resolution perimetry.在光感、闪烁和分辨率视野检查中出现的弥漫性和局限性青光眼性视野缺损。
Graefes Arch Clin Exp Ophthalmol. 1991;229(3):267-73. doi: 10.1007/BF00167882.
9
Comparison of retinal nerve-fiber layer in high- and normal-tension glaucoma.高眼压性青光眼与正常眼压性青光眼视网膜神经纤维层的比较。
Graefes Arch Clin Exp Ophthalmol. 1991;229(6):517-20. doi: 10.1007/BF00203313.