Scott J A, Palmer E L, Fischman A J, Strauss H W
Department of Radiology, Massachusetts General Hospital, Boston 02114.
Invest Radiol. 1992 Aug;27(8):583-6. doi: 10.1097/00004424-199208000-00005.
Reports published earlier this century suggested that meteorologic factors influence the incidence of pulmonary embolism. These observations were based on few patients and often lacked rigorous standards of evidence. In the current study, the authors evaluate the association between barometric pressure changes and pulmonary embolism using radionuclide ventilation-perfusion (V/Q) scan data.
Daily interpretation data for V/Q lung scans were correlated retrospectively with daily local barometric pressure changes over a 7-year period.
The incidence of pulmonary embolic disease was significantly related to a decrease in barometric pressure during the 3 days preceding clinical presentation.
Meteorologic factors are less important than better-known risk factors for pulmonary embolism; however, their effect is demonstrable in a large data sample. This work confirms previously published associations between barometric pressure changes and the incidence of pulmonary embolism.
本世纪早期发表的报告表明，气象因素会影响肺栓塞的发病率。这些观察基于少数患者，且往往缺乏严格的证据标准。在本研究中，作者使用放射性核素通气灌注（V/Q）扫描数据评估气压变化与肺栓塞之间的关联。
对7年间V/Q肺扫描的每日解读数据与每日当地气压变化进行回顾性关联分析。
肺栓塞疾病的发病率与临床表现前3天的气压下降显著相关。
气象因素在肺栓塞中不如广为人知的风险因素重要；然而，在大数据样本中其影响是可证实的。这项工作证实了先前发表的气压变化与肺栓塞发病率之间的关联。
