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正常人类胎儿合成的巨球蛋白抗体的特异性。

SPECIFICITY OF MACROGLOBULIN ANTIBODY SYNTHESIZED BY THE NORMAL HUMAN FETUS.

作者信息

EPSTEIN W V

出版信息

Science. 1965 Jun 18;148(3677):1591-2. doi: 10.1126/science.148.3677.1591.

DOI:10.1126/science.148.3677.1591
PMID:14287601
Abstract

The umbilical cord blood of 47 out of 54 normal human infants contains hemagglutinating activity directed toward cells coated with a type-L Bence-Jones protein. This hemagglutinating material, in some instances, is present in cord blood in the absence of such activity in the maternal blood. Ultracentrifugation of cord serum in a sucrose gradient shows that the activity is associated with the macroglobulin fractions.

摘要

54名正常人类婴儿中,47名的脐带血含有针对L型本-周蛋白包被细胞的血凝活性。在某些情况下,这种血凝物质在脐带血中存在,而母血中却没有这种活性。在蔗糖梯度中对脐带血清进行超速离心表明,该活性与巨球蛋白组分有关。

相似文献

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SPECIFICITY OF MACROGLOBULIN ANTIBODY SYNTHESIZED BY THE NORMAL HUMAN FETUS.正常人类胎儿合成的巨球蛋白抗体的特异性。
Science. 1965 Jun 18;148(3677):1591-2. doi: 10.1126/science.148.3677.1591.
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Naturally-occurring macroglobulin antibody of foetal origin in the normal human newborn.正常人类新生儿中天然存在的胎儿源性巨球蛋白抗体。
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引用本文的文献

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Anti-IgG agglutinins in idiopathic respiratory distress syndrome of the newborn.新生儿特发性呼吸窘迫综合征中的抗IgG凝集素
Arch Dis Child. 1969 Dec;44(238):747-56. doi: 10.1136/adc.44.238.747.
2
Immunological diseases and pregnancy.免疫性疾病与妊娠
Br Med J. 1966 Jun 25;1(5503):1559-67. doi: 10.1136/bmj.1.5503.1559.
3
Naturally-occurring macroglobulin antibody of foetal origin in the normal human newborn.正常人类新生儿中天然存在的胎儿源性巨球蛋白抗体。
Immunology. 1966 Mar;10(3):259-70.
4
Distribution of malarial antibody in maternal and cord sera.疟疾抗体在母体血清和脐带血清中的分布。
Arch Dis Child. 1969 Aug;44(236):511-4. doi: 10.1136/adc.44.236.511.
5
Lymphocytes with membrane-bound immunoglobulin (B-lymphocytes) in new-born babies.新生婴儿中带有膜结合免疫球蛋白的淋巴细胞(B淋巴细胞)。
Clin Exp Immunol. 1972 Aug;11(4):495-505.
6
The development of immunity in fetal life and childhood.胎儿期及儿童期免疫的发育
J R Coll Physicians Lond. 1972 Apr;6(3):246-58.
7
Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. II. Determination of frequency and characteristics of idiotypic T and B lymphocytes in normal rats using direct visualization.针对相同抗原决定簇的B淋巴细胞和T淋巴细胞上的共享独特型决定簇。II. 使用直接可视化方法测定正常大鼠中独特型T淋巴细胞和B淋巴细胞的频率及特征
J Exp Med. 1975 Nov 1;142(5):1218-30. doi: 10.1084/jem.142.5.1218.