Gabellini A S, Pezzoli A, De Massis P, Sacquegna T
Servizio di Neurologia, Ospedale Maggiore di Bologna.
Ital J Neurol Sci. 1992 Oct;13(7):621-3. doi: 10.1007/BF02233409.
Veralipride is a benzamide derivative effective in the treatment of menopausal syndrome. Despite its antidopaminergic action, extrapyramidal side effects seem to be very uncommon. We observed a patient with bipolar psychosis, who developed segmental dystonia after taking the drug. The disorder slowly receded in 14 months, but reappeared during neuroleptic therapy a few months later. To the best of our knowledge, this is the first case of veralipride-induced tardive dystonia, and the affective disorder might have predisposed our patient to the development of this tardive side effect.
维拉必利是一种对治疗更年期综合征有效的苯甲酰胺衍生物。尽管它具有抗多巴胺能作用，但锥体外系副作用似乎非常罕见。我们观察到一名双相情感障碍精神病患者，在服用该药物后出现了节段性肌张力障碍。这种病症在14个月内逐渐消退，但在几个月后的抗精神病药物治疗期间再次出现。据我们所知，这是首例由维拉必利引起的迟发性肌张力障碍，而情感障碍可能使我们的患者易患这种迟发性副作用。
