Fiedor L, Rosenbach-Belkin V, Scherz A
Department of Biochemistry, Weizmann Institute of Science, Rehovot, Israel.
J Biol Chem. 1992 Nov 5;267(31):22043-7.
Chlorophyllase-catalyzed hydrolysis and esterification of chlorophylls, bacteriochlorophylls, and their free acids, respectively, depend on the configuration around the C-13(2) atom of the corresponding substrate. The data suggest that the enzyme interacts preferentially with compounds having the isocyclic carbomethoxy and the C-17 propionic residues facing opposite sides of the porphyrin macrocycle. The relevance of this observation to chlorophyll biosynthesis and degradation in vivo is briefly discussed.
