Van Dorp C S, Ten Cate J M
Department of Cariology and Endodontology, Academic Centre for Dentistry (ACTA), Amsterdam, The Netherlands.
ASDC J Dent Child. 1992 Jul-Aug;59(4):257-62.
The aim of this study was to compare pit-and fissure sealants with fluoride treatments in their effectiveness to inhibit or reduce the progression of enamel lesions, particularly in the fissure region. The effects of fissure probing as used in diagnosis were compared with in the same protocol. Using a combination of image analysis of X-ray pictures of full crowns and a light microscopic evaluation of cross-sections provided information on the three dimensional spread of enamel demineralization. Pit-and-fissure sealants were superior in protecting enamel against progression of demineralization, as long as the walls of the fissures were well covered. The protection against demineralization offered by fluoride was mainly restricted to the smooth enamel surfaces; in fissures no protection could be measured. Surface defects of the enamel caused by probing or abrasion aided the progress of the lesion.
本研究的目的是比较窝沟封闭剂与氟化物治疗在抑制或减少釉质病变进展方面的有效性，特别是在窝沟区域。将诊断中使用的窝沟探查效果按照相同方案进行比较。结合全冠X线片的图像分析和横断面的光学显微镜评估，提供了关于釉质脱矿三维扩散的信息。只要窝沟壁得到良好覆盖，窝沟封闭剂在保护釉质防止脱矿进展方面更具优势。氟化物提供的防脱矿作用主要局限于光滑的釉质表面；在窝沟中未检测到保护作用。探查或磨损引起的釉质表面缺陷会加速病变进展。
