Brown M L
Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, MD 20892.
J Gerontol. 1992 Nov;47 Spec No:51-8.
The incidence of breast cancer increases with age, tending to result in more favorable cost-effectiveness outcomes with more advanced age of the screened population. On the other hand, the decreased remaining life expectancy of older women can be expected to reduce the cost effectiveness of screening. To assess these competing factors, the cost effectiveness of a long-term breast cancer screening program was evaluated using a computerized simulation model. The cost per life year saved decreased when the 65-69 year age group was added to a program screening women aged 50-64. For older age groups, however, cost effectiveness became relatively less favorable. The cost per life year saved of screening the 80-84 year age group was 55% higher than for the 65-69 group.
乳腺癌的发病率随年龄增长而上升，筛查人群年龄越大，成本效益结果往往越有利。另一方面，老年女性预期剩余寿命的缩短预计会降低筛查的成本效益。为了评估这些相互矛盾的因素，使用计算机模拟模型对长期乳腺癌筛查项目的成本效益进行了评估。当将65 - 69岁年龄组纳入50 - 64岁女性的筛查项目时，每挽救一个生命年的成本降低。然而，对于年龄较大的年龄组，成本效益相对变得不那么有利。筛查80 - 84岁年龄组每挽救一个生命年的成本比65 - 69岁组高55%。
