Suppr超能文献

[肥厚型心肌病的功能特征]

[Functional characteristics of hypertrophic cardiomyopathy].

作者信息

Tomov I, Savova A

出版信息

Vutr Boles. 1977;16(1):17-27.

PMID:143130
Abstract

The hemodynamics was studies in 59 patients with hypertrophic cardiopathy: obstructive (33 cases) and non-obstructive (26 cases). The diagnosis was made and the hemodynamics studied by left and right ventricle catheterization, left ventriculography and echocardiography. A general hyperkinetism of the left ventricle pump function was established--increased fraction of forcing, per cent of the systolic shortening and contraction rate of the circumferential fibres with a not adequately large beat and minute volume. The regional functional of the left ventricle is characterized by hypokinetism of the interventricular septum and considerable hypercontractility of the left ventricle free wall. The diastolic filling of the left ventricle is impeded due to the decreased telediastolic size and volume and diminished extensibility. That leads to the increase of the final diastolic pressure in the left ventricle and the pulmonary artery, manifested especially after physical loading. The subaortic constriction is a result mainly of the systolic shifting of the posterior papillaris muscle forward and upward towards the hypertrophic interventricular septum. Subaortic stenosis shows considerable deviations and changes during the dynamic observations of the patients.

摘要

对59例肥厚型心肌病患者的血流动力学进行了研究:梗阻性(33例)和非梗阻性(26例)。通过左右心室导管检查、左心室造影和超声心动图进行诊断并研究血流动力学。确立了左心室泵功能的普遍运动亢进——射血分数增加、收缩期缩短百分比和圆周纤维收缩率增加,但心搏量和分钟量不够大。左心室的区域功能特点是室间隔运动减弱和左心室游离壁明显过度收缩。由于舒张末期大小和容积减小以及伸展性降低,左心室的舒张期充盈受到阻碍。这导致左心室和肺动脉的舒张末期压力升高,尤其在体力负荷后表现明显。主动脉下狭窄主要是后乳头肌在收缩期向前向上向肥厚的室间隔移位的结果。在对患者进行动态观察期间,主动脉下狭窄显示出相当大的偏差和变化。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验