Drăgulescu S I, Streian C, Mourtada A, Shencoru F
Med Interne. 1980 Oct-Dec;18(4):371-5.
Abnormal thickening and limited or eccentric mobility of the aortic leaflets were used as indicators of the aortic stenosis (AS). The magnitude of ventricular hypertrophy in response to afterloading was determined by wall stress, with wall thickness. Measures of the echocardiographic internal dimensions of the left ventricle, wall thickness and circumferential fiber shortening (Vcf), were able to characterize left ventricular function in 13 patients with AS. In moderate and severe AS with normal left ventricular function, left ventricular end-diastolic dimension (Dd) was normal, posterior wall thickness (Wt) increased and myocardial contraction (Vcf) was normal. In patients with left ventricular failure, Dd was increased and myocardial contraction markedly depressed. Echocardiography is a noninvasive method for estimating the severity of aortic stenosis and it appears to be more sensitive than other currently employed techniques.
主动脉瓣叶增厚异常以及活动受限或偏心运动被用作主动脉瓣狭窄（AS）的指标。后负荷引起的心室肥厚程度由壁应力和壁厚度决定。通过测量左心室的超声心动图内径、壁厚度和圆周纤维缩短率（Vcf），能够对13例AS患者的左心室功能进行表征。在左心室功能正常的中度和重度AS患者中，左心室舒张末期内径（Dd）正常，后壁厚度（Wt）增加，心肌收缩（Vcf）正常。在左心室衰竭患者中，Dd增加，心肌收缩明显减弱。超声心动图是一种用于评估主动脉瓣狭窄严重程度的非侵入性方法，并且似乎比目前使用的其他技术更敏感。
