组胺在伤口愈合中的作用 一、高剂量组胺对伤口中胶原蛋白和糖胺聚糖含量的影响
The role of histamine in wound healing I. The effect of high doses of histamine on collagen and glycosoaminoglycan content in wounds.
作者信息
Dabrowski R, Maśliński C, Olczak A
出版信息
Agents Actions. 1977 Jul;7(2):219-24. doi: 10.1007/BF01969976.
PMID:143201
Abstract
The effect of high doses of histamine (Hi) on collagen and glycosoaminoglycan (GAG) content in skin wounds of rats was studied on days 1, 3, 5, 10 and 14 after wounding. Injection of high doses of Hi into the wounded area inhibited colagen production, collagen polymerization and GAG synthesis; levels of chondroitin sulphates (chondroitin-4,6-sulphate and dermatan sulphate) and hyaluronic acid were decreased.
摘要
在受伤后的第1、3、5、10和14天，研究了高剂量组胺（Hi）对大鼠皮肤伤口中胶原蛋白和糖胺聚糖（GAG）含量的影响。向伤口区域注射高剂量的Hi会抑制胶原蛋白的产生、胶原蛋白聚合和GAG合成；硫酸软骨素（硫酸软骨素-4,6-硫酸盐和硫酸皮肤素）和透明质酸的水平降低。
Zotero 插件