Gastaud M, Dolisi C, Camous J P, Gibelli A, Ozon C, Ardisson J L
C R Seances Soc Biol Fil. 1977;171(1):169-75.
In the dog under pentobarbitone anesthesia, the intravenous infusion of 1 mg/kg S 2620 results in tachycardia and systemic arterial hypertension. The same attenuated effects are caused by a second injection of the drug after cervical vagotomy and chemoreceptors denervation. Tachycardia and peripheral vaso constriction can account for elevation of arterial pressure.
