Woo J, Lau E, Chan A, Cockram C, Swaminathan R
Department of Medicine, Chinese University, Hong Kong.
J Hum Hypertens. 1992 Aug;6(4):299-304.
The prevalence of hypertension and the relationship between blood pressure, age, body mass index (BMI) and urinary cations from casual urine specimens were examined in 1,513 Chinese employees of a public utility company and non-medical personnel of a district hospital. The prevalence of hypertension, defined as systolic blood pressure greater than or equal to 140 or a diastolic blood pressure greater than or equal to 90 mmHg, or a past history of hypertension, was 17% in men and 5% in women. After excluding subjects who were on antihypertensive medication, age, body mass index, and urinary sodium/potassium ratio were independently and positively associated with blood pressure, while urinary potassium/creatinine ratio was inversely related to blood pressure. No association with urinary sodium or sodium/creatinine ratio was found. Higher mean blood pressure in men was accompanied by lower urinary potassium/creatinine and potassium concentration and higher sodium/potassium ratio, even though men had the same mean BMI when compared with women. A difference in potassium intake between the sexes may partly account for this finding. We conclude that in this Chinese population, whose dietary intake is more influenced by the West compared with Chinese in the Peoples' Republic of China, age and BMI are important determinants of blood pressure, together with potassium intake as reflected by urinary potassium excretion. No association of blood pressure with sodium excretion was demonstrated.
在一家公用事业公司的1513名中国员工以及一家区级医院的非医务人员中,研究了高血压患病率以及随意尿样中血压、年龄、体重指数(BMI)与尿阳离子之间的关系。高血压的定义为收缩压大于或等于140mmHg或舒张压大于或等于90mmHg,或有高血压病史,男性患病率为17%,女性为5%。排除正在服用抗高血压药物的受试者后,年龄、体重指数和尿钠/钾比值与血压呈独立正相关,而尿钾/肌酐比值与血压呈负相关。未发现与尿钠或钠/肌酐比值有关联。尽管男性与女性的平均BMI相同,但男性较高的平均血压伴随着较低的尿钾/肌酐和钾浓度以及较高的钠/钾比值。两性之间钾摄入量的差异可能部分解释了这一发现。我们得出结论,在这群饮食摄入比中华人民共和国的中国人受西方影响更大的中国人群中,年龄和BMI是血压的重要决定因素,同时尿钾排泄所反映的钾摄入量也很重要。未证明血压与钠排泄有关联。