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精索静脉曲张治疗:三种方法的前瞻性随机试验

Varicocele treatment: prospective randomized trial of 3 methods.

作者信息

Sayfan J, Soffer Y, Orda R

机构信息

Department of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

出版信息

J Urol. 1992 Nov;148(5):1447-9. doi: 10.1016/s0022-5347(17)36934-3.

DOI:10.1016/s0022-5347(17)36934-3
PMID:1433548
Abstract

This study was done to evaluate the surgical results and the impact on fertility potential of 3 methods of varicocele treatment. Consecutive varicocele patients with primary or secondary infertility were randomly assigned to 3 treatment groups. Of the patients 36 underwent percutaneous embolization, 55 high ligation of the internal spermatic vein and 28 transinguinal simultaneous ligation of the internal and external spermatic veins. The transinguinal ligation proved to be safe. There was no difference in pregnancy rates but the seminal variables showed a slight improvement with statistical significance only in the 2 open surgical methods. There were no surgical failures in the transinguinal group as opposed to the other 2 techniques. Transinguinal ligation of the internal and external spermatic veins may be recommended as the primary treatment for varicocele. This technique also seems to be the procedure of choice when repeat intervention is required for failure of high ligation or embolization.

摘要

本研究旨在评估3种精索静脉曲张治疗方法的手术效果及其对生育潜能的影响。将原发性或继发性不育的连续精索静脉曲张患者随机分为3个治疗组。其中36例患者接受经皮栓塞治疗,55例接受精索内静脉高位结扎术,28例接受经腹股沟精索内、外静脉同时结扎术。经腹股沟结扎术被证明是安全的。妊娠率无差异,但精液参数仅在2种开放手术方法中有轻微改善且具有统计学意义。与其他2种技术不同,经腹股沟组未出现手术失败情况。经腹股沟精索内、外静脉结扎术可作为精索静脉曲张的首选治疗方法。当高位结扎或栓塞失败需要再次干预时,该技术似乎也是首选的手术方式。

相似文献

1
Varicocele treatment: prospective randomized trial of 3 methods.精索静脉曲张治疗:三种方法的前瞻性随机试验
J Urol. 1992 Nov;148(5):1447-9. doi: 10.1016/s0022-5347(17)36934-3.
2
Spermatic vein ligation as treatment for male infertility. Justification by postoperative semen improvement and pregnancy rates.精索静脉结扎术治疗男性不育症。术后精液改善情况及妊娠率作为其合理性依据。
J Reprod Med. 1990 Feb;35(2):123-7.
3
Intraoperative internal spermatic vein phlebography in the subfertile male with varicocele.精索静脉曲张所致男性不育患者的术中精索内静脉静脉造影术。
Fertil Steril. 1978 Jun;29(6):669-75. doi: 10.1016/s0015-0282(16)43343-1.
4
Efficacy of varicocele embolization versus ligation of the left internal spermatic vein for improvement of sperm quality.
Int J Androl. 1992 Aug;15(4):338-44. doi: 10.1111/j.1365-2605.1992.tb01133.x.
5
Surgical ligation vs. angiographic embolization of the vena spermatica: a prospective randomized study for the treatment of varicocele-related infertility.精索静脉手术结扎与血管造影栓塞术对比:一项治疗精索静脉曲张相关性不育的前瞻性随机研究
Andrologia. 1993 Sep-Oct;25(5):233-7. doi: 10.1111/j.1439-0272.1993.tb02716.x.
6
Low-grade left varicocele in patients over 30 years old:the effect of spermatic vein ligation on fertility.
BJU Int. 2000 Feb;85(3):305-7. doi: 10.1046/j.1464-410x.2000.00437.x.
7
High ligation or embolization of varicocele.
Isr J Med Sci. 1986 Dec;22(12):877-9.
8
Clinical outcome and cost comparison of percutaneous embolization and surgical ligation of varicocele.
J Androl. 1994 Nov-Dec;15 Suppl:38S-42S.
9
Further observations on the role of varicocele in human male infertility.关于精索静脉曲张在男性不育症中作用的进一步观察
Fertil Steril. 1969 Jul-Aug;20(4):545-63. doi: 10.1016/s0015-0282(16)37081-9.
10
Clinical versus subclinical varicocele: venographic findings and improvement of fertility after embolization.
Radiology. 1985 Jun;155(3):635-8. doi: 10.1148/radiology.155.3.4001363.

引用本文的文献

1
Comparison of sclero-embolization and surgical ligation for varicocele treatment: a systematic review and meta-analysis.
World J Urol. 2025 Oct 25;43(1):627. doi: 10.1007/s00345-025-06014-4.
2
Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data.精索静脉曲张修复术能否改善传统精液参数?一项前后数据的荟萃分析研究。
World J Mens Health. 2024 Jan;42(1):92-132. doi: 10.5534/wjmh.230034. Epub 2023 Jun 22.
3
Surgical or radiological treatment for varicoceles in subfertile men.对不育男性精索静脉曲张的手术或放射治疗。
Cochrane Database Syst Rev. 2021 Apr 23;4(4):CD000479. doi: 10.1002/14651858.CD000479.pub6.
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Varicocele.精索静脉曲张
BMJ Clin Evid. 2015 Jul 13;2015:1806.
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Effect of varicocelectomy on male infertility.精索静脉曲张切除术对男性不育症的影响。
Korean J Urol. 2014 Nov;55(11):703-9. doi: 10.4111/kju.2014.55.11.703. Epub 2014 Nov 10.
6
Inguinal and subinguinal micro-varicocelectomy, the optimal surgical management of varicocele: a meta-analysis.腹股沟和腹股沟下显微精索静脉结扎术,精索静脉曲张的最佳手术治疗方法:一项荟萃分析
Asian J Androl. 2015 Jan-Feb;17(1):74-80. doi: 10.4103/1008-682X.136443.
7
Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized clinical trials.手术治疗精索静脉曲张对临床诊断为精索静脉曲张且精液质量受损的不育男性妊娠率的影响:一项随机临床试验的荟萃分析
Korean J Urol. 2013 Oct;54(10):703-9. doi: 10.4111/kju.2013.54.10.703. Epub 2013 Oct 15.
8
The great debate: varicocele treatment and impact on fertility.精索静脉曲张的治疗及其对生育能力的影响:一场大辩论
Fertil Steril. 2011 Mar 1;95(3):841-52. doi: 10.1016/j.fertnstert.2011.01.002. Epub 2011 Jan 26.
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Varicocele.精索静脉曲张
BMJ Clin Evid. 2009 Jan 6;2009:1806.
10
Transcatheter therapeutic embolization of genitourinary pathology.泌尿生殖系统疾病的经导管治疗性栓塞术
Rev Urol. 2000 Fall;2(4):236-52.