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精索静脉手术结扎与血管造影栓塞术对比:一项治疗精索静脉曲张相关性不育的前瞻性随机研究

Surgical ligation vs. angiographic embolization of the vena spermatica: a prospective randomized study for the treatment of varicocele-related infertility.

作者信息

Nieschlag E, Behre H M, Schlingheider A, Nashan D, Pohl J, Fischedick A R

机构信息

Institute of Reproductive Medicine, The University, Münster, Germany.

出版信息

Andrologia. 1993 Sep-Oct;25(5):233-7. doi: 10.1111/j.1439-0272.1993.tb02716.x.

DOI:10.1111/j.1439-0272.1993.tb02716.x
PMID:8250285
Abstract

Varicoceles as a common cause of male infertility are treated either by surgical ligation or, more recently, by angiographic occlusion of the spermatic vein. In the present prospective randomized study 38 patients were treated by surgical ligation and 33 by angiographic embolization. During the 12-month follow-up period a significant increase in sperm number (at 3 and 12 months) and sperm motility (at 12 months) occurred in both groups while sperm morphology remained unaffected. Altogether, 22 pregnancies (31%) were reported within the year following treatment, of which 11/38 (29%) occurred in the ligation group and 11/33 (33%) in the embolization group. Thus both treatment modalities appear equivalent, whereby embolization has the advantage that it can be performed on an outpatient basis.

摘要

精索静脉曲张作为男性不育的常见原因,可通过手术结扎治疗,或者最近采用的精索静脉血管造影闭塞术治疗。在本前瞻性随机研究中,38例患者接受了手术结扎治疗,33例接受了血管造影栓塞治疗。在12个月的随访期内,两组患者的精子数量(3个月和12个月时)和精子活力(12个月时)均显著增加,而精子形态未受影响。治疗后一年内共报告了22例妊娠(31%),其中结扎组为11/38(29%),栓塞组为11/33(33%)。因此,两种治疗方式似乎等效,而栓塞术的优势在于可在门诊进行。

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1
Surgical ligation vs. angiographic embolization of the vena spermatica: a prospective randomized study for the treatment of varicocele-related infertility.精索静脉手术结扎与血管造影栓塞术对比:一项治疗精索静脉曲张相关性不育的前瞻性随机研究
Andrologia. 1993 Sep-Oct;25(5):233-7. doi: 10.1111/j.1439-0272.1993.tb02716.x.
2
Update on treatment of varicocele: counselling as effective as occlusion of the vena spermatica.精索静脉曲张治疗的最新进展:咨询与精索静脉闭塞效果相同。
Hum Reprod. 1998 Aug;13(8):2147-50. doi: 10.1093/humrep/13.8.2147.
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[Embolization of the spermatic vein in 42 patients with decreased fertility and a varicocele].[42例生育力下降且患有精索静脉曲张患者的精索静脉栓塞术]
Ned Tijdschr Geneeskd. 1984 Feb 25;128(8):344-50.
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Balloon occlusion of the internal spermatic vein for the treatment of varicoceles.精索内静脉球囊闭塞术治疗精索静脉曲张。
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Post-surgical recurrent varicocele: efficacy of internal spermatic venography and steel-coil embolization.
Br J Urol. 1996 Jan;77(1):124-8. doi: 10.1046/j.1464-410x.1996.82321.x.
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Controlled trial of high spermatic vein ligation for varicocele in infertile men.精索静脉曲张高位结扎术治疗男性不育症的对照试验
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Percutaneous sclerotherapy for varicocele embolization.
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Ligation of the left spermatic vein in the treatment of male infertility.左侧精索静脉结扎术治疗男性不育症。
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Surgery or embolization for varicoceles in subfertile men.对不育男性精索静脉曲张进行手术或栓塞治疗。
Cochrane Database Syst Rev. 2012 Oct 17;10:CD000479. doi: 10.1002/14651858.CD000479.pub5.
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Low-grade left varicocele in patients over 30 years old:the effect of spermatic vein ligation on fertility.
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引用本文的文献

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Surgical or radiological treatment for varicoceles in subfertile men.对不育男性精索静脉曲张的手术或放射治疗。
Cochrane Database Syst Rev. 2021 Apr 23;4(4):CD000479. doi: 10.1002/14651858.CD000479.pub6.
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Contribution to the Pathophysiology and Treatment of Varicoceles.精索静脉曲张的病理生理学及治疗研究进展
J Belg Soc Radiol. 2018 Feb 9;102(1):22. doi: 10.5334/jbr-btr.1453.
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Percutaneous embolization of varicocele: technique, indications, relative contraindications, and complications.精索静脉曲张的经皮栓塞术:技术、适应证、相对禁忌证及并发症
Asian J Androl. 2016 Mar-Apr;18(2):234-8. doi: 10.4103/1008-682X.169985.
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Varicocele.精索静脉曲张
BMJ Clin Evid. 2015 Jul 13;2015:1806.
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Effect of varicocelectomy on male infertility.精索静脉曲张切除术对男性不育症的影响。
Korean J Urol. 2014 Nov;55(11):703-9. doi: 10.4111/kju.2014.55.11.703. Epub 2014 Nov 10.
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Inguinal and subinguinal micro-varicocelectomy, the optimal surgical management of varicocele: a meta-analysis.腹股沟和腹股沟下显微精索静脉结扎术,精索静脉曲张的最佳手术治疗方法:一项荟萃分析
Asian J Androl. 2015 Jan-Feb;17(1):74-80. doi: 10.4103/1008-682X.136443.
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Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized clinical trials.手术治疗精索静脉曲张对临床诊断为精索静脉曲张且精液质量受损的不育男性妊娠率的影响:一项随机临床试验的荟萃分析
Korean J Urol. 2013 Oct;54(10):703-9. doi: 10.4111/kju.2013.54.10.703. Epub 2013 Oct 15.
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Gonadal vein embolization: treatment of varicocele and pelvic congestion syndrome.性腺静脉栓塞术:精索静脉曲张和盆腔淤血综合征的治疗
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