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1
Education of lymphocytes in vivo following a transient take of a matched unrelated bone-marrow graft in man.人类接受匹配的无关供者骨髓移植后短暂植活情况下淋巴细胞的体内培养。
Clin Exp Immunol. 1977 Aug;29(2):266-71.
2
Direct and antibody-dependent cell-mediated cytotoxicity against HLA identical sibling lymphocytes. Correlation with marrow graft rejections.针对 HLA 相同同胞淋巴细胞的直接及抗体依赖细胞介导的细胞毒性。与骨髓移植排斥反应的相关性。
Transplantation. 1976 Dec;22(6):631-5.
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[In vivo detection of alloreactive T cells of host origin after rejection of HLA-identical allogeneic bone marrow transplant].[HLA 同基因异基因骨髓移植排斥后宿主来源同种反应性 T 细胞的体内检测]
Schweiz Med Wochenschr. 1985 Oct 26;115(43):1525-6.
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CD6+ T cell depleted allogeneic bone marrow transplantation from genotypically HLA nonidentical related donors.来自基因分型 HLA 不相同的相关供体的 CD6+ T 细胞耗竭的异基因骨髓移植。
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Bone marrow transplantation for aplastic anaemia from a HL-A and MLC-identical unrelated donor.来自人类白细胞抗原（HL-A）和混合淋巴细胞培养（MLC）匹配的无关供者的再生障碍性贫血的骨髓移植。
Blut. 1975 Dec;31(6):347-54. doi: 10.1007/BF01634000.
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Identification of unrelated HLA-identical bone marrow donors: RFLP, oligotyping and PCR fingerprinting for HLA class II compared to MLC responses.无关的HLA匹配骨髓供者的鉴定：与混合淋巴细胞培养反应相比，HLAⅡ类的限制性片段长度多态性分析、寡核苷酸分型及PCR指纹分析
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本文引用的文献

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Serotyping for homotransplantation. 18. Refinement of microdroplet lymphocyte cytotoxicity test.同种移植的血清分型。18. 微滴淋巴细胞细胞毒性试验的改进。
Transplantation. 1968 Nov;6(8):913-27. doi: 10.1097/00007890-196811000-00006.
2
Mixed lymphocyte cultures produce effector cells: model in vitro for allograft rejection.混合淋巴细胞培养产生效应细胞：同种异体移植排斥的体外模型。
Science. 1970 Apr 3;168(3927):133-5. doi: 10.1126/science.168.3927.133.
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A method for preparing buffy coat-poor blood for transfusion. A modification.
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Gnotobiotic care of patients with immunologic deficiency diseases.
Transplant Proc. 1973 Sep;5(3):1271-7.
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Marrow transplantation for the treatment of acute leukemia using HL-A-identical siblings.
Transplant Proc. 1974 Dec;6(4):365-6.
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Marrow transplantation in aplastic anemia.再生障碍性贫血的骨髓移植
Transplant Proc. 1974 Dec;6(4):355-8.
7
Effect of prior blood transfusions on marrow grafts: abrogation of sensitization by procarbazine and antithymocyte serum.既往输血对骨髓移植的影响：丙卡巴肼和抗胸腺细胞血清消除致敏作用
J Immunol. 1974 Apr;112(4):1508-16.
8
Three closely linked genetic systems relevant to transplantation.与移植相关的三个紧密相连的遗传系统。
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3031-5. doi: 10.1073/pnas.68.12.3031.
9
Marrow transplanation in man following cyclophosphamide.环磷酰胺治疗后人类的骨髓移植
Transplant Proc. 1971 Mar;3(1):400-4.
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Methotrexate regimens for control of graft-versus-host disease in dogs with allogeneic marrow grafts.
Transplantation. 1970 Mar;9(3):240-6. doi: 10.1097/00007890-197003000-00007.

人类接受匹配的无关供者骨髓移植后短暂植活情况下淋巴细胞的体内培养。

Education of lymphocytes in vivo following a transient take of a matched unrelated bone-marrow graft in man.

作者信息

Goldmann S F, Kristensen T, Grunnet N, Lohrmann H P, Heimpel H, Kissmeyer-Nielsen F

出版信息

Clin Exp Immunol. 1977 Aug;29(2):266-71.

PMID:143356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1541087/
Abstract

A patient suffering from aplastic anaemia was treated by bone-marrow transplantation from an ABO- and HLA-identical, MLC- and CML-negative, unrelated donor. MLC and CML became positive after transplantation indicating that a cellular immune response had developed against lymphocyte determinants not recognized prior to sensitization in vivo. Whether these determinants are governed by genes of the HLA region is unknown at present.

摘要

一名再生障碍性贫血患者接受了来自 ABO 和 HLA 匹配、MLC 和 CML 阴性的无关供体的骨髓移植。移植后 MLC 和 CML 呈阳性，表明针对体内致敏前未识别的淋巴细胞决定簇产生了细胞免疫反应。目前尚不清楚这些决定簇是否受 HLA 区域基因的控制。