Lieske J C, Spargo B H, Toback F G
Department of Medicine, University of Chicago, Illinois 60637.
J Urol. 1992 Nov;148(5):1517-9. doi: 10.1016/s0022-5347(17)36954-9.
A patient with primary hyperoxaluria who received a liver-kidney transplant is presented. A postoperative renal biopsy showed apparent tubular cell endocytosis of calcium oxalate crystals and cell proliferation, indicating that renal epithelial cells do not perceive urinary crystals as inert. Such cellular responses to crystals may have a role in nephrolithiasis.
本文介绍了一名接受肝肾移植的原发性高草酸尿症患者。术后肾活检显示草酸钙晶体明显被肾小管细胞内吞且细胞增殖，这表明肾上皮细胞并不将尿结晶视为惰性物质。这种细胞对晶体的反应可能在肾结石形成中起作用。
