Khan S R, Hackett R L
Department of Pathology, College of Medicine, University of Florida, Gainesville 32610.
Scanning Microsc. 1991 Sep;5(3):707-11; discussion 711-2.
Crystal retention within the renal tubules is essential for nephrolithiasis and the development of urinary stone disease. We studied the mechanisms involved in this process by inducing calcium oxalate crystal deposition within the rat renal tubules and examining them using various microscopic techniques. Crystals appeared to be retained either by attachment to the tubular epithelium or by aggregating with other crystals thus becoming large enough to be retained by their collective size.
肾小管内的晶体潴留对于肾结石和泌尿系统结石疾病的发展至关重要。我们通过诱导大鼠肾小管内草酸钙晶体沉积，并使用各种显微镜技术对其进行检查，研究了这一过程中涉及的机制。晶体似乎通过附着于肾小管上皮或与其他晶体聚集从而变得足够大以因其总体大小而被潴留。
