因使用氟他胺治疗前列腺癌继发的近乎致命的肝功能障碍。

Near fatal liver dysfunction secondary to administration of flutamide for prostate cancer.

作者信息

Dankoff J S

机构信息

Department of Urology, Northeastern Ohio Universities, College of Medicine, Akron.

出版信息

J Urol. 1992 Dec;148(6):1914. doi: 10.1016/s0022-5347(17)37071-4.

DOI:10.1016/s0022-5347(17)37071-4

PMID:1433640

Abstract

A 66-year-old man with metastatic prostate cancer was treated with bilateral orchiectomy and 750 mg. flutamide per day. Near fatal liver dysfunction developed 10 weeks later. Flutamide was discontinued and 8 weeks later liver enzymes had returned to normal.

摘要

一名66岁的转移性前列腺癌男性患者接受了双侧睾丸切除术，并每天服用750毫克氟他胺。10周后出现了近乎致命的肝功能障碍。停用氟他胺，8周后肝酶恢复正常。