小鼠植入前胚胎在体外的类固醇代谢
Steroid metabolism by mouse preimplantation embryos in vitro.
作者信息
Antila E, Koskinen J, Niemela P, Saure A
出版信息
Experientia. 1977 Oct 15;33(10):1374-5. doi: 10.1007/BF01920189.
PMID:143370
Abstract
Mouse preimplantation embryos were incubated with radioactive pregnenolone, progesterone or dehydroepiandrosterone for various periods of time. These substrates were not converted to metabolites even after incubation of 120 h. We suggest that preimplantation mouse embryo does not possess enzyme activities for steroid metabolism.
摘要
将小鼠植入前胚胎与放射性孕烯醇酮、孕酮或脱氢表雄酮孵育不同时间。即使孵育120小时后，这些底物也未转化为代谢产物。我们认为植入前小鼠胚胎不具备类固醇代谢的酶活性。
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