Neppert B, Guthoff R, Heidemann H T
Universitäts-Augenklinik Hamburg.
Klin Monbl Augenheilkd. 1992 Aug;201(2):122-4. doi: 10.1055/s-2008-1045881.
We report this exemplary case of a drug addict with candida endophthalmitis where we used the new form of amphotericin B, encapsulated in liposomes. We were able to reconfirm the reduced number of side effects and the minimized nephrotoxicity reported by authors of other specialties. In our patient, a reduction or elimination of the yeast was probably achieved, nevertheless, he developed a traction retinal detachment. In future cases of fungal endophthalmitis, we recommend liposomal amphotericin B in higher doses.
我们报告了一例药物成瘾者患念珠菌性眼内炎的典型病例,在此病例中我们使用了脂质体包裹的新型两性霉素B。我们能够再次证实其他专业领域作者所报道的副作用数量减少以及肾毒性降至最低。在我们的患者中,可能实现了酵母菌数量的减少或消除,然而,他却发生了牵引性视网膜脱离。在未来真菌性眼内炎的病例中,我们建议使用更高剂量的脂质体两性霉素B。