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一种用于肝移植大鼠胆管吻合及肝内间隔胆汁收集的简易方法。

A simple method for bile duct anastomosis and interval bile collection in the liver-transplanted rat.

作者信息

Xu H S, Rosenlof L K, Selby J B, Jones R S

机构信息

Department of Surgery, University of Virginia Health Sciences Center, Charlottesville 22908.

出版信息

J Surg Res. 1992 Nov;53(5):520-3. doi: 10.1016/0022-4804(92)90100-e.

DOI:10.1016/0022-4804(92)90100-e
PMID:1434603
Abstract

A mini T-tube is introduced for the bile duct anastomosis of rat liver transplantation as well as interval bile collection. The validity of the T-tube was evaluated in 14 liver-transplanted rats and compared to 14 rats using traditional stent for bile duct anastomosis. Changes of biliary tree after the T-tube anastomosis were examined by T-tube cholangiography on sample rats at 4 days and at 4 months after liver grafting. Additionally, bile volumes and rates of bile salt secretion were compared in the continuously flowing cannula and the chronic T-tube fistula in normal rats. The results show that the mini T-tube facilitates bile duct anastomosis and study of bile secretion after liver transplantation in rats without increase in surgical difficulty or interference of biliary enterohepatic circulation.

摘要

一种微型T管被用于大鼠肝移植的胆管吻合以及间歇性胆汁收集。在14只肝移植大鼠中评估了T管的有效性,并与14只使用传统支架进行胆管吻合的大鼠进行了比较。在肝移植后4天和4个月,通过对样本大鼠进行T管胆管造影检查T管吻合术后胆管树的变化。此外,还比较了正常大鼠连续流动插管和慢性T管瘘中的胆汁量和胆汁盐分泌率。结果表明,微型T管有助于大鼠肝移植后的胆管吻合和胆汁分泌研究,且不会增加手术难度或干扰胆汁肠肝循环。

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1
A simple method for bile duct anastomosis and interval bile collection in the liver-transplanted rat.一种用于肝移植大鼠胆管吻合及肝内间隔胆汁收集的简易方法。
J Surg Res. 1992 Nov;53(5):520-3. doi: 10.1016/0022-4804(92)90100-e.
2
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引用本文的文献

1
Physiologic study of bile salt and lipid secretion in rats after liver transplantation.肝移植后大鼠胆汁盐和脂质分泌的生理学研究
Ann Surg. 1993 Apr;217(4):404-12. doi: 10.1097/00000658-199304000-00013.
2
Bile secretion and liver regeneration in partially hepatectomized rats.部分肝切除大鼠的胆汁分泌与肝再生
Ann Surg. 1993 Aug;218(2):176-82. doi: 10.1097/00000658-199308000-00009.
3
Study of donor-recipient liver size match for transplantation.肝移植供受体肝脏大小匹配的研究。
Ann Surg. 1994 Jan;219(1):46-50. doi: 10.1097/00000658-199401000-00008.
4
Prostaglandin E1 increases survival with extended anhepatic phase during liver transplantation.前列腺素E1可提高肝移植期间无肝期延长时的生存率。
Ann Surg. 1994 Jul;220(1):53-8. doi: 10.1097/00000658-199407000-00009.