Nicholson C P, Allen M S, Trastek V F, Tazelaar H D, Pairolero P C
Department of Surgery, Mayo Clinic, Rochester, MN 55905.
Mayo Clin Proc. 1992 Jul;67(7):646-50. doi: 10.1016/s0025-6196(12)60718-6.
Dirofilariasis is an unusual but increasing cause of solitary pulmonary nodules. In this study, we reviewed the entire experience with dirofilariasis at our institution. Five such patients were identified. In all patients, the Dirofilaria immitis infection manifested as a solitary pulmonary nodule, and all patients underwent thoracotomy for diagnosis. None required systemic treatment. D. immitis is found in dog, cat, wolf, coyote, and fox populations throughout the United States, but the highest concentrations have been noted in the eastern, southeastern, and southern coastal states. The distribution of human cases of D. immitis infection has a similar pattern. Pulmonary dirofilariasis should be included in the differential diagnosis of peripheral noncalcified pulmonary nodules, especially in endemic areas.
犬恶丝虫病是孤立性肺结节的一个不常见但发病率呈上升趋势的病因。在本研究中，我们回顾了我院犬恶丝虫病的全部诊疗经验。共识别出5例此类患者。在所有患者中，犬恶丝虫感染均表现为孤立性肺结节，且所有患者均接受了开胸手术以明确诊断。无一例需要全身治疗。在美国各地的犬、猫、狼、郊狼和狐狸种群中均发现有犬恶丝虫，但在东部、东南部和南部沿海各州的感染浓度最高。犬恶丝虫感染的人类病例分布也有类似模式。肺犬恶丝虫病应纳入外周非钙化性肺结节的鉴别诊断，尤其是在流行地区。
