Hoang T K, Bronshteĭn A M, Nguyen V D, Nguyen V T, Nguyen T Z, Sabgaĭda T P
Med Parazitol (Mosk). 1992 Jul-Aug(4):11-3.
An intensive focus of intestinal nematodiases in a foothill province of Vietnam is described; the incidence of ascaridiasis there was found to be 81.8%, trichuriasis 78.1%, and ankylostomiasis 12.3%. Polyinvasions were detected in more than 80% of the examinees. Analysis of five schemes of medamin therapy, used in three provinces in 595 patients with ascaridiasis, 490 ones with trichuriasis, and 323 ones with ankylostomiasis has shown that the treatment efficacy was reducing with the invasion intensity augmentation. In ascariasis the 3- and 5-day therapeutic schemes were the most effective, their efficacies being 68.4 and 82.0%, respectively; in trichuriasis and ankylostomiasis a 3-day scheme was the best, its efficacies being 74.0 and 71.9%, respectively. Retrograde ascarid migration occurred in 1.2% of 595 ascaridiasis patients after medamin therapy.
描述了越南一个山麓省份肠道线虫病的集中发病情况；发现该地区蛔虫病发病率为81.8%，鞭虫病为78.1%，钩虫病为12.3%。在80%以上的受检者中检测到多重感染。对在三个省份用于595例蛔虫病患者、490例鞭虫病患者和323例钩虫病患者的五种美达明治疗方案进行分析后发现，随着感染强度增加，治疗效果降低。在蛔虫病中，3天和5天治疗方案最有效，有效率分别为68.4%和82.0%；在鞭虫病和钩虫病中，3天方案最佳，有效率分别为74.0%和71.9%。在595例蛔虫病患者接受美达明治疗后，1.2%出现蛔虫逆行迁移。
