Hoang T K, Bronshteĭn A M, Nguyen T Z, Nguyen V T, Sabgaĭda T P
Med Parazitol (Mosk). 1993 Mar-Apr(2):27-8.
Comparative trials of pirantel analogs--combatrin (Pfizer, Philippines) and embovin (Russia) were carried out in a hyperendemic focus of intestinal nematodoses in Vietnam. The drugs were prescribed in a single dose of 10 mg/kg. No significant differences in the efficacies of the drugs were revealed: combatrin and embovin efficacies in ascariasis were 94.3 and 98.0%, respectively (p > 0.05), in ankylostomiasis 76.3 and 58.3%, respectively (p > 0.05).
对越南肠道线虫病高度流行区进行了吡喹酮类似物——复方甲苯咪唑(辉瑞公司,菲律宾)和恩波维铵(俄罗斯)的对比试验。药物采用10毫克/千克单剂量给药。未发现药物疗效有显著差异:复方甲苯咪唑和恩波维铵治疗蛔虫病的疗效分别为94.3%和98.0%(p>0.05),治疗钩虫病的疗效分别为76.3%和58.3%(p>0.05)。