Nikolić-Vukosavljević D, Branković-Magić M, Polić D, Vlajić M, Vuletić L, Spuzić I
Institute of Oncology and Radiology, Beograd, Serbia.
Neoplasma. 1992;39(5):299-304.
The purpose of this study was to investigate whether histologic type and grade of primary breast cancer are related to the estrogen and progesterone receptors. Our results showed that histologic type influenced the estrogen dependence through histologic grade. There was no difference in the estrogen and progesterone receptor content, when corresponding grades of different histologic types and estrogen dependence were confirmed by quantitative non-parametric analysis. It showed a direct relationship between estrogen and progesterone receptor content in all the three histologic grades and further that histologic grade defines three different groups in regard to progesterone receptor content.
本研究的目的是调查原发性乳腺癌的组织学类型和分级是否与雌激素和孕激素受体相关。我们的结果表明，组织学类型通过组织学分级影响雌激素依赖性。当通过定量非参数分析确认不同组织学类型和雌激素依赖性的相应分级时，雌激素和孕激素受体含量没有差异。结果显示，在所有三种组织学分级中，雌激素和孕激素受体含量之间存在直接关系，并且进一步表明，就孕激素受体含量而言，组织学分级定义了三个不同的组。
