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[家兔个体发育过程中眼组织的糖酵解。I. 糖酵解和磷酸己糖旁路的酶]

[Glycolysis in the eye tissues of the rabbit in ontogeny. I. The enzymes of glycolysis and hexosemonophosphate shunt].

作者信息

Faustov V S

出版信息

Ontogenez. 1977;8(4):361-9.

PMID:143640
Abstract

The activity of the enzymes of glycolysis (phosphofructokinase, aldolase, pyruvate kinase, lactate dehydrogenase) and hexose monophosphate shunt (glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase) was determined in the eye tissues of the rabbit at different stages of ontogenesis. The activity of these enzymes in the retina was shown to be higher than in other eye tissues. In the uveal tract (iris, ciliary bodies, uvea) the activity of glycolytic enzymes changes with the age. The greatest changes in the activity of enzymes were found during the period of the opening of eyelids. The activity of the enzymes of hexose monophosphate shunt in the eye tissues increases with the age. The relative activity of dehydrogenases of the hexose monophosphate shunt after the establishment of visual function is, however, not high and does not exceed that of phosphofructokinase and pyruvate kinase in the eye tissues of the rabbit.

摘要

在兔眼组织发育的不同阶段,测定了糖酵解(磷酸果糖激酶、醛缩酶、丙酮酸激酶、乳酸脱氢酶)和磷酸己糖旁路(葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶)中酶的活性。结果表明,视网膜中这些酶的活性高于其他眼组织。在葡萄膜(虹膜、睫状体、脉络膜)中,糖酵解酶的活性随年龄变化。酶活性的最大变化发生在眼睑张开期。眼组织中磷酸己糖旁路酶的活性随年龄增加。然而,视觉功能建立后,磷酸己糖旁路脱氢酶的相对活性不高,不超过兔眼组织中磷酸果糖激酶和丙酮酸激酶的活性。

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