Fink B A, Carney L G, Hill R M
College of Optometry, Ohio State University, Columbus.
Optom Vis Sci. 1992 Sep;69(9):691-7. doi: 10.1097/00006324-199209000-00004.
Differences between corneal oxygen uptake rates measured after 5 min of static (without blinking) and 5 min of dynamic (with blinking once every 5 s) non-gas permeable (polymethyl methacrylate) contact lens wear, referenced to the oxygen uptake rates of the normal open eye, were used as indications of tear pump efficiencies associated with each of seven contact lens back vertex powers (-9.00 to +9.00 D, in 3.00 D steps). Measurements were made in vivo on six human corneas showing with-the-rule (0.25 to 0.87 D) toricity. Lens overall diameter was 8.8 mm, optic zone diameter was 7.4 mm, and base curve radius was fitted "on K." Lens center thickness was 0.14 mm for all minus-powered lenses, and 0.19, 0.26, 0.34, and 0.41 mm for the plano, +3.00, +6.00, and +9.00 D lenses, respectively, maintaining an edge thickness of 0.11 mm. Under both static and dynamic wearing conditions, no significant differences were found among the corneal oxygen uptake rates associated with the various contact lens back vertex powers; however, the difference between the static and dynamic condition data, an indication of tear pump efficiency, was greatest for the -3.00 D lens. The difference values associated with the +9.00 and +6.00 D lenses were significantly lower than those associated with the minus power lenses.
以正常睁眼的氧摄取率为参照，测量了佩戴非透气（聚甲基丙烯酸甲酯）隐形眼镜5分钟静态（不眨眼）和5分钟动态（每5秒眨眼一次）后的角膜氧摄取率差异，以此作为七种不同后顶点屈光度（-9.00至+9.00 D，间隔3.00 D）隐形眼镜各自相关的泪液泵效率指标。对六只呈现顺规性（0.25至0.87 D）散光的人眼角膜进行了体内测量。镜片总直径为8.8 mm，光学区直径为7.4 mm，基弧半径根据角膜曲率进行适配。所有负屈光度镜片的镜片中心厚度为0.14 mm，平光、+3.00、+6.00和+9.00 D镜片的中心厚度分别为0.19、0.26、0.34和0.41 mm，边缘厚度保持为0.11 mm。在静态和动态佩戴条件下，不同后顶点屈光度隐形眼镜相关的角膜氧摄取率之间均未发现显著差异；然而，作为泪液泵效率指标的静态和动态条件数据之间的差异，在-3.00 D镜片中最大。与+9.00和+6.00 D镜片相关的差异值显著低于与负屈光度镜片相关的差异值。
