Allwood M C, Greenwood M
Medicines Research Unit, Derbyshire College of Higher Education, Mickleover, Derby, United Kingdom.
Pharm Weekbl Sci. 1992 Oct 16;14(5):321-4. doi: 10.1007/BF01977621.
The application of X-ray energy dispersive spectroscopy to detect elements collected from TPN mixtures on membrane filters has been investigated. Many simple total parenteral nutrition mixtures prepared aseptically in large bags can be stored for extended periods. Trace elements are normally excluded from such bags, because not enough is known about their long-term stability and compatibility in total parenteral nutrition mixtures. Assessing the compatibility of many trace elements by conventional methods that rely on detecting concentration changes is extremely difficult. Analysis of precipitates from total parenteral nutrition mixtures confirmed that the proposed method was capable of identifying a number of elements from the mixture in complex precipitates, including calcium, phosphorus, iron, copper and selenium.
研究了应用X射线能量色散光谱法检测膜滤器上从全胃肠外营养（TPN）混合物中收集的元素。许多在大袋子中无菌制备的简单全胃肠外营养混合物可以长期储存。微量元素通常不包含在这类袋子中，因为对于它们在全胃肠外营养混合物中的长期稳定性和兼容性了解不足。通过依赖检测浓度变化的传统方法评估许多微量元素的兼容性极其困难。对全胃肠外营养混合物中的沉淀物进行分析证实，所提出的方法能够从复杂沉淀物中的混合物中识别出多种元素，包括钙、磷、铁、铜和硒。
