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嗜酸性粒细胞增多性肺浸润(肺嗜酸性粒细胞增多症)

[Pulmonary infiltrations with eosinophilia (pulmonary eosinophilia)].

作者信息

Fischer B M, Schadmand S, Gerharz C D, Steppling H, Ferlinz R

机构信息

III. Medizinische Klinik-Schwerpunkt Pneumoloige, Johannes Gutenberg Universität Mainz.

出版信息

Pneumologie. 1992 Sep;46(9):476-83.

PMID:1438127
Abstract

The pulmonary eosinophilias are characterised by radiographic lung shadows with either a peripheral blood eosinophilia of more than 450/microliter or histologic abnormalities consisting of both interstitial and intraalveolar accumulations of eosinophils and macrophages. We describe the clinical features, radiographic changes, results of bronchoscopy and follow-up studies of three women with chronic eosinophilic pneumonia of unknown aetiology. In all patients the illness resolved rapidly after treatment with corticosteroids, however one patient experienced a second episode after treatment withdrawal. We demonstrate the wide differential diagnosis of the syndrome of pulmonary eosinophilia.

摘要

肺嗜酸性粒细胞增多症的特征是胸部X光片上出现肺部阴影,同时外周血嗜酸性粒细胞计数超过450/微升,或组织学异常,表现为嗜酸性粒细胞和巨噬细胞在间质和肺泡内积聚。我们描述了三名病因不明的慢性嗜酸性粒细胞性肺炎女性患者的临床特征、影像学变化、支气管镜检查结果及随访研究。所有患者经皮质类固醇治疗后病情迅速缓解,但有一名患者在停药后复发。我们展示了肺嗜酸性粒细胞增多症综合征的广泛鉴别诊断。

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