Lu W X
Peking Union Medical College Hospital, Beijing.
Zhonghua Jie He He Hu Xi Za Zhi. 1990 Feb;13(1):12-4, 60-1.
A case of chronic eosinophilic pneumonia (CEP), confirmed by transfibroptic bronchoscope lung biopsy, was reported. CEP is a chronic interstitial lung disease characterized by cough, dyspnea, malaise, fever, night sweats, weight loss, variable degree of blood eosinophilia and film revealing peripheral nonsegmental nonmigratory infiltrates. It usually responds dramatically to corticosteroids. The authors suggested that a tentative diagnosis is often made on clinical grounds only without biopsy confirmation and corticosteroid therapy is instituted. It is necessary to perform lung biopsy for establishing the diagnosis when the patient has normal eosinophilic count, nonpheripheral lung infiltrats or other atypical manifestations.
报告了一例经纤维支气管镜肺活检确诊的慢性嗜酸性粒细胞性肺炎(CEP)。CEP是一种慢性间质性肺疾病,其特征为咳嗽、呼吸困难、不适、发热、盗汗、体重减轻、不同程度的血液嗜酸性粒细胞增多以及影像学显示外周非节段性、不游走性浸润。它通常对皮质类固醇治疗反应显著。作者指出,往往仅基于临床情况做出初步诊断而未进行活检确认,就开始进行皮质类固醇治疗。当患者嗜酸性粒细胞计数正常、肺部浸润不在外周或有其他非典型表现时,有必要进行肺活检以明确诊断。