Dubiel J S, Petkow-Dimitrow P, Reichhart J, Jurczak W, Zmudka K
II Kliniki Kardiologii Instytutu Kardiologii Akademii Medycznej, Krakowie.
Przegl Lek. 1992;49(3):73-5.
The aim of our studies was to estimate the relation between the reduction of the subendocardial blood flow, expressed by DPTI/TTI ratio and the grade of aortic stenosis determined by the maximal systolic aortic gradient. Additionally the influence of subendocardial blood flow reduction of left ventricular function and ECG alterations was assessed. The analyzed data were obtained during the cardiac catheterizations in a group of 30 patients (average age 32 years). The mean value of DPTI/TTI ratio was decreased (0.49 +/- 0.2) and associated with the elevated mean value of AGmax (72.2 +/- 38.1 mmHg). Negative correlation between DPTI/TTI and AGmax (r = -0.73; p less than 0.003), DPTI/TTI and LVEDP (r = -0.53; p less than 0.005) occurred. Depression of ST-T segment in EEG and episodes of anginal pain accompanied the reduction of subendocardial blood flow. We concluded that reduction in subendocardial blood flow in patients with SA-may lead subendocardial ischaemia of the left ventricular wall with subsequent of its function.
我们研究的目的是评估以DPTI/TTI比值表示的心内膜下血流减少与由最大收缩期主动脉梯度确定的主动脉狭窄程度之间的关系。此外，还评估了心内膜下血流减少对左心室功能和心电图改变的影响。分析的数据来自一组30例患者（平均年龄32岁）的心导管检查。DPTI/TTI比值的平均值降低（0.49±0.2），并与AGmax的升高平均值（72.2±38.1 mmHg）相关。DPTI/TTI与AGmax之间呈负相关（r = -0.73；p<0.003），DPTI/TTI与LVEDP之间呈负相关（r = -0.53；p<0.005）。脑电图ST-T段压低和心绞痛发作伴随着心内膜下血流减少。我们得出结论，SA患者的心内膜下血流减少可能导致左心室壁心内膜下缺血，继而影响其功能。
